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FoxO3a Modulates Hypoxia Stress Induced Oxidative Stress and Apoptosis in Cardiac Microvascular Endothelial Cells

Cardiac microvascular endothelial cells (CMECs) dysfunction induced by hypoxia is an important pathophysiological event in myocardium ischemic injury, whereas, the underlying mechanism is not fully clarified. FoxO transcription factors regulate target genes involved in apoptosis and cellular reactiv...

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Autors principals: Zhang, Shenwei, Zhao, Yilin, Xu, Ming, Yu, Li, Zhao, Yujie, Chen, Jianghong, Yuan, Yiqiang, Zheng, Qiangsun, Niu, Xiaolin
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835407/
https://ncbi.nlm.nih.gov/pubmed/24278276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080342
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