Endothelial dysfunction occurs prior to clinical evidence of Polycystic Kidney Disease

OBJECTIVE: Polycystic kidney disease (PKD), a monogenic disease with an autosomal dominant or an autosomal recessive form of inheritance (ARPKD), is the most common genetic cause of renal dysfunction and end stage renal failure. In addition to the development of cysts, the autosomal form of PKD is a...

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Autori principali: Peterson, Karen M., Franchi, Federico, Loeffler, Darrel L., Psaltis, Peter J., Harris, Peter C., Lerman, Lilach O., Lerman, Amir, Rodriguez-Porcel, Martin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835344/
https://ncbi.nlm.nih.gov/pubmed/24008943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000354236
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