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Blood-brain barrier impairment in MPS III patients

BACKGROUND: Mucopolysaccharidosis type III (MPS III) is an autosomal recessive disorder caused by deficiency of a specific enzyme leading to heparan sulfate (HS) accumulation within cells and to eventual progressive cerebral and systemic organ abnormalities. Different enzyme deficiencies comprise th...

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Detalles Bibliográficos
Main Authors: Garbuzova-Davis, Svitlana, Mirtyl, Santhia, Sallot, Sebastian A, Hernandez-Ontiveros, Diana G, Haller, Edward, Sanberg, Paul R
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835134/
https://ncbi.nlm.nih.gov/pubmed/24225396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2377-13-174
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