Overexpression of MMP-7 increases collagen 1A2 in the aging kidney

The percentage of the U.S. population over 65 is rapidly increasing, as is the incidence of chronic kidney disease (CKD). The kidney is susceptible to age-dependent alterations in structure, specifically tubulointerstitial fibrosis that leads to CKD. Matrix metalloproteinases (MMPs) were initially c...

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Bibliographic Details
Main Authors: Ślusarz, Anna, Nichols, LaNita A, Grunz-Borgmann, Elizabeth A, Chen, Gang, Akintola, Adebayo D, Catania, Jeffery M, Burghardt, Robert C, Trzeciakowski, Jerome P, Parrish, Alan R
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2013
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834982/
https://ncbi.nlm.nih.gov/pubmed/24273653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/phy2.90
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