Overexpression of MMP-7 increases collagen 1A2 in the aging kidney

The percentage of the U.S. population over 65 is rapidly increasing, as is the incidence of chronic kidney disease (CKD). The kidney is susceptible to age-dependent alterations in structure, specifically tubulointerstitial fibrosis that leads to CKD. Matrix metalloproteinases (MMPs) were initially c...

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Detalhes bibliográficos
Main Authors: Ślusarz, Anna, Nichols, LaNita A, Grunz-Borgmann, Elizabeth A, Chen, Gang, Akintola, Adebayo D, Catania, Jeffery M, Burghardt, Robert C, Trzeciakowski, Jerome P, Parrish, Alan R
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834982/
https://ncbi.nlm.nih.gov/pubmed/24273653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/phy2.90
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