Overexpression of MMP-7 increases collagen 1A2 in the aging kidney

The percentage of the U.S. population over 65 is rapidly increasing, as is the incidence of chronic kidney disease (CKD). The kidney is susceptible to age-dependent alterations in structure, specifically tubulointerstitial fibrosis that leads to CKD. Matrix metalloproteinases (MMPs) were initially c...

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Bibliografiske detaljer
Main Authors: Ślusarz, Anna, Nichols, LaNita A, Grunz-Borgmann, Elizabeth A, Chen, Gang, Akintola, Adebayo D, Catania, Jeffery M, Burghardt, Robert C, Trzeciakowski, Jerome P, Parrish, Alan R
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2013
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834982/
https://ncbi.nlm.nih.gov/pubmed/24273653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/phy2.90
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