Drug Adverse Event Detection in Health Plan Data Using the Gamma Poisson Shrinker and Comparison to the Tree-based Scan Statistic

Background: Drug adverse event (AE) signal detection using the Gamma Poisson Shrinker (GPS) is commonly applied in spontaneous reporting. AE signal detection using large observational health plan databases can expand medication safety surveillance. Methods: Using data from nine health plans, we cond...

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Huvudupphovsmän: Brown, Jeffrey S., Petronis, Kenneth R., Bate, Andrew, Zhang, Fang, Dashevsky, Inna, Kulldorff, Martin, Avery, Taliser R., Davis, Robert L., Chan, K. Arnold, Andrade, Susan E., Boudreau, Denise, Gunter, Margaret J., Herrinton, Lisa, Pawloski, Pamala A., Raebel, Marsha A., Roblin, Douglas, Smith, David, Reynolds, Robert
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2013
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834945/
https://ncbi.nlm.nih.gov/pubmed/24300404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics5010179
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