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In Vivo Tumor Targeting and Image-Guided Drug Delivery with Antibody-Conjugated, Radiolabeled Mesoporous Silica Nanoparticles

Since the first use of biocompatible mesoporous silica (mSiO(2)) nanoparticles as drug delivery vehicles, in vivo tumor targeted imaging and enhanced anti-cancer drug delivery has remained a major challenge. In this work, we describe the development of functionalized mSiO(2) nanoparticles for active...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Feng, Hong, Hao, Zhang, Yin, Valdovinos, Hector F., Shi, Sixiang, Kwon, Glen S., Theuer, Charles P., Barnhart, Todd E., Cai, Weibo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834886/
https://ncbi.nlm.nih.gov/pubmed/24083623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn403617j
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