Aminoacylation and translational quality control strategy employed by leucyl-tRNA synthetase from a human pathogen with genetic code ambiguity

Aminoacyl-tRNA synthetases should ensure high accuracy in tRNA aminoacylation. However, the absence of significant structural differences between amino acids always poses a direct challenge for some aminoacyl-tRNA synthetases, such as leucyl-tRNA synthetase (LeuRS), which require editing function to...

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Dettagli Bibliografici
Autori principali: Zhou, Xiao-Long, Fang, Zhi-Peng, Ruan, Zhi-Rong, Wang, Meng, Liu, Ru-Juan, Tan, Min, Anella, Fabrizio Maria, Wang, En-Duo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2013
Soggetti:
Nucleic Acid Enzymes
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834818/
https://ncbi.nlm.nih.gov/pubmed/23969415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt741
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