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Uninfected vertebrate cells contain a protein that is closely related to the product of the avian sarcoma virus transforming gene (src).

Neoplastic transformation of cell by avian sarcoma virus is mediated by a single viral gene (src), which encodes a phosphoprotein (pp60src) with the enzymatic activity of a protein kinase. The DNAs of vertebrate species contain a highly conserved homologue of src that is also represented in the poly...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Oppermann, H, Levinson, A D, Varmus, H E, Levintow, L, Bishop, J M
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1979
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383480/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/221907/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.4.1804
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