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VBP1 facilitates proteasome and autophagy-mediated degradation of MutS homologue hMSH4

Ubiquitination is an important mechanism for the regulation of diverse cellular functions, including proteolysis and DNA repair. The human MutS family protein hMSH4 functions in meiotic recombinational DNA double-strand break (DSB) repair. It was previously observed that hMSH4 interacts with the von...

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Detalhes bibliográficos
Main Authors: Xu, Yang, Her, Chengtao
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834780/
https://ncbi.nlm.nih.gov/pubmed/23964080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-235127
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