Potent humanin analog increases glucose-stimulated insulin secretion through enhanced metabolism in the β cell

Humanin (HN) is a 24-aa polypeptide that offers protection from Alzheimer's disease and myocardial infarction, increases insulin sensitivity, improves survival of β cells, and delays onset of diabetes. Here we examined the acute effects of HN on insulin secretion and potential mechanisms throug...

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Detalhes bibliográficos
Main Authors: Kuliawat, Regina, Klein, Laura, Gong, Zhenwei, Nicoletta-Gentile, Marianna, Nemkal, Anjana, Cui, Lingguang, Bastie, Claire, Su, Kai, Huffman, Derek, Surana, Manju, Barzilai, Nir, Fleischer, Norman, Muzumdar, Radhika
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2013
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834779/
https://ncbi.nlm.nih.gov/pubmed/23995290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-231092
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