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Peptide nucleic acids inhibit growth of Brucella suis in pure culture and in infected murine macrophages
Peptide nucleic acids (PNAs) are single-stranded, synthetic nucleic acid analogues containing a pseudopeptide backbone in place of the phosphodiester sugar–phosphate. When PNAs are covalently linked to cell-penetrating peptides (CPPs) they readily penetrate the bacterial cell envelope, inhibit expre...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3834731/ https://ncbi.nlm.nih.gov/pubmed/23305655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijantimicag.2012.11.017 |
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