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Positive control of lac operon expression in vitro by guanosine 5′-diphosphate 3′-diphosphate

Maximal expression of the Escherichia coli lactose operon in a coupled in vitro transcription-translation system from a Salmonella typhimurium relA mutant was strongly dependent upon addition of guanosine 5′-diphosphate 3′-diphosphate (ppGpp). Without added ppGpp, at saturating 3′,5′-cyclic AMP (cAM...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Primakoff, Paul, Artz, Stanley W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1979
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383463/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/109832/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.4.1726
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