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Micronucleus Test of Picrorrhiza Rhizoma Aqueous Extract in Bone Marrow Cells of Male ICR Mice

In this research, the genotoxic effect of Picrorrhiza Rhizoma (PR) aqueous extract was evaluated using the mouse micronucleus test. PR extract was administered once a day for 2 continuous days by oral gavage to male ICR mice at doses of 2000, 1000 and 500 mg/kg. Cyclophosphamide was used as a known...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chung, In-Kwon, Cheon, Woo-Hyun, Ku, Sae-Kwang
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Korean Society of Toxicology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834366/
https://ncbi.nlm.nih.gov/pubmed/24278560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5487/TR.2011.27.2.119
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