Inhibition of Cell Adhesion by an Anti-cadherin 11 Antibody Prevents Bone Metastasis

Cadherin-11 is a member of a superfamily mainly expressed in osteoblasts but not in epithelial cells. However, prostate cancer (PCa) cells with bone metastasis propensity express high levels of cadherin-11 and reduced levels of E-cadherin. Downregulation of cadherin-11 inhibits interaction of PCa ce...

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Autores principales: Lee, Yu-Chen, Bilen, Mehmet Asim, Yu, Guoyu, Lin, Song-Chang, Huang, Chih-Fen, Ortiz, Angelica, Cho, Hyojin, Song, Jian H., Satcher, Robert L., Kuang, Jian, Gallick, Gary E., Yu-Lee, Li-Yuan, Huang, Wilber, Lin, Sue-Hwa
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834228/
https://ncbi.nlm.nih.gov/pubmed/23913163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-13-0108
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