Evaluation of Potential Ionizing Irradiation Protectors and Mitigators Using Clonogenic Survival of Human Umbilical Cord Blood Hematopoietic Progenitor Cells

We evaluated the use of colony formation (CFU-GM, BFU-E, and CFU-GEMM) by human umbilical cord blood (CB) hematopoietic progenitor cells for testing novel small molecule ionizing irradiation protectors and mitigators. Each of 11 compounds was added before (protection) or after (mitigation) ionizing...

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Main Authors: Goff, Julie P., Shields, Donna S., Wang, Hong, Skoda, Erin M., Sprachman, Melissa M., Wipf, Peter, Garapati, Venkata Krishna, Atkinson, Jeffrey, London, Barry, Lazo, John S., Kagan, Valerian, Epperly, Michael W., Greenberger, Joel S.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834150/
https://ncbi.nlm.nih.gov/pubmed/23933481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2013.08.001
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