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Indistinguishable Synaptic Pharmacodynamics of the N-Methyl-d-Aspartate Receptor Channel Blockers Memantine and Ketamine

Memantine and ketamine, voltage- and activation-dependent channel blockers of N-methyl-d-aspartate (NMDA) receptors (NMDARs), have enjoyed a recent resurgence in clinical interest. Steady-state pharmacodynamic differences between these blockers have been reported, but it is unclear whether the compo...

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Main Authors: Emnett, Christine M., Eisenman, Lawrence N., Taylor, Amanda M., Izumi, Yukitoshi, Zorumski, Charles F., Mennerick, Steven
פורמט: Artigo
שפה:Inglês
יצא לאור: The American Society for Pharmacology and Experimental Therapeutics 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834148/
https://ncbi.nlm.nih.gov/pubmed/24101301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.113.089334
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