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RNA-Sequencing Quantification of Hepatic Ontogeny of Phase-I Enzymes in Mice
Phase-I drug metabolizing enzymes catalyze reactions of hydrolysis, reduction, and oxidation of drugs and play a critical role in drug metabolism. However, the functions of most phase-I enzymes are not mature at birth, which markedly affects drug metabolism in newborns. Therefore, characterization o...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The American Society for Pharmacology and Experimental Therapeutics
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3834128/ https://ncbi.nlm.nih.gov/pubmed/24080161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.113.054635 |
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