Role of iron in the pathogenesis of cysteamine-induced duodenal ulceration in rats

Cysteamine induces perforating duodenal ulcers in rats within 24–48 h. This reducing aminothiol generates hydrogen peroxide in the presence of transition metals (e.g., ferric iron), producing oxidative stress, which may contribute to organ-specific tissue damage. Since most intestinal iron absorptio...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Khomenko, Tetyana, Szabo, Sandor, Deng, Xiaoming, Ishikawa, Hideki, Anderson, Gregory J., McLaren, Gordon D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2009
Pynciau:
Mucosal Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834006/
https://ncbi.nlm.nih.gov/pubmed/19342511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90257.2008
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