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Role of iron in the pathogenesis of cysteamine-induced duodenal ulceration in rats
Cysteamine induces perforating duodenal ulcers in rats within 24–48 h. This reducing aminothiol generates hydrogen peroxide in the presence of transition metals (e.g., ferric iron), producing oxidative stress, which may contribute to organ-specific tissue damage. Since most intestinal iron absorptio...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Physiological Society
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3834006/ https://ncbi.nlm.nih.gov/pubmed/19342511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90257.2008 |
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