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Regulation of liver hepcidin expression by alcohol in vivo does not involve Kupffer cell activation or TNF-α signaling

Alcohol downregulates hepcidin expression in the liver leading to an increase in intestinal iron transport and liver iron storage. We have previously demonstrated that alcohol-mediated oxidative stress is involved in the inhibition of hepcidin transcription by alcohol in vivo. Kupffer cells and TNF-...

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Detalhes bibliográficos
Main Authors: Harrison-Findik, Duygu Dee, Klein, Elizabeth, Evans, John, Gollan, John
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833991/
https://ncbi.nlm.nih.gov/pubmed/19008338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90550.2008
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