Development of a method to isolate circulating tumor cells using mesenchymal-based capture

Epithelial tumor cells can become mesenchymal cells and vice versa via phenotypic transitions, a process known as epithelial plasticity. We postulate that during the process of metastasis, circulating tumor cells (CTCs) lose their epithelial phenotype and acquire a mesenchymal phenotype that may not...

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Main Authors: Bitting, Rhonda L., Boominathan, Rengasamy, Rao, Chandra, Kemeny, Gabor, Foulk, Brad, Garcia-Blanco, Mariano A., Connelly, Mark, Armstrong, Andrew J.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833983/
https://ncbi.nlm.nih.gov/pubmed/23845299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2013.06.034
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