Distribution of interleukin-1-immunoreactive microglia in cerebral cortical layers: implications for neuritic plaque formation in Alzheimer’s disease

Activated microglia overexpressing interleukin-1 (IL-1) are prominent neuropathological features of Alzheimer’s disease. We used computerized image analysis to determine the number of IL-1α-immunoreactive (IL-1α(+)) microglia in cytoarchitectonic layers of parahippocampal gyrus (Brodmann’s area 28)...

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Main Authors: Sheng, J. G., Griffin, W. S. T., Royston, M.C., Mrak, R. E.
Format: Artigo
Sprog:Inglês
Udgivet: 1998
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833591/
https://ncbi.nlm.nih.gov/pubmed/9775393
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