The serotonin-2 receptor modulator, (−)-trans-PAT, decreases voluntary ethanol consumption in rats

Serotonin (5-HT) 5-HT(2C) receptor agonists have shown promise as novel alcoholism pharmacotherapies, but developing selective agonists has been problematic. Female Sprague Dawley rats were given ethanol in a palatable gel vehicle during operant sessions. 5-HT(2C) receptor modulators (Ro60-0175, SB2...

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Detalhes bibliográficos
Main Authors: Kasper, James, Tikamdas, Rajiv, Kim, Myong Sang, MacFadyen, Kaley, Aramini, Richard, Ladd, Joseph, Bisceglia, Sarah, Booth, Raymond, Peris, Joanna
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833445/
https://ncbi.nlm.nih.gov/pubmed/24041931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2013.09.008
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