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Par3 controls neural crest migration by promoting microtubule catastrophe during contact inhibition of locomotion

There is growing evidence that contact inhibition of locomotion (CIL) is essential for morphogenesis and its failure is thought to be responsible for cancer invasion; however, the molecular bases of this phenomenon are poorly understood. Here we investigate the role of the polarity protein Par3 in C...

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Autors principals: Moore, Rachel, Theveneau, Eric, Pozzi, Sara, Alexandre, Paula, Richardson, Joanna, Merks, Anne, Parsons, Maddy, Kashef, Jubin, Linker, Claudia, Mayor, Roberto
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833433/
https://ncbi.nlm.nih.gov/pubmed/24173803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.098509
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