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Hippo signaling impedes adult heart regeneration

Heart failure due to cardiomyocyte loss after ischemic heart disease is the leading cause of death in the United States in large part because heart muscle regenerates poorly. The endogenous mechanisms preventing mammalian cardiomyocyte regeneration are poorly understood. Hippo signaling, an ancient...

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Main Authors: Heallen, Todd, Morikawa, Yuka, Leach, John, Tao, Ge, Willerson, James T., Johnson, Randy L., Martin, James F.
格式: Artigo
語言:Inglês
出版: Company of Biologists 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833428/
https://ncbi.nlm.nih.gov/pubmed/24255096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.102798
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