Mechanisms for Human Atrial Fibrillation Initiation: Clinical and Computational Studies of Repolarization Restitution and Activation Latency

BACKGROUND: Mechanisms of atrial fibrillation (AF) initiation are incompletely understood. We hypothesized that rate-dependent changes (restitution) in action potential duration (APD) and activation latency are central targets for clinical interventions that induce AF. We tested this hypothesis usin...

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Главные авторы: Krummen, David E., Bayer, Jason D., Ho, Jeffrey, Ho, Gordon, Smetak, Miriam R., Clopton, Paul, Trayanova, Natalia A., Narayan, Sanjiv M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833353/
https://ncbi.nlm.nih.gov/pubmed/23027797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCEP.111.969022
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