Intratumoral regulatory T cells upregulate immunosuppressive molecules in head and neck cancer patients

BACKGROUND: Although regulatory T cells (Treg) are highly enriched in human tumours compared with peripheral blood, expression of the immune-checkpoint receptors, immunosuppressive molecules and function of Treg in these two sites remains undefined. METHODS: Tumour-infiltrating lymphocytes and perip...

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Detalhes bibliográficos
Main Authors: Jie, H-B, Gildener-Leapman, N, Li, J, Srivastava, R M, Gibson, S P, Whiteside, T L, Ferris, R L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833228/
https://ncbi.nlm.nih.gov/pubmed/24169351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.645
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