ALK gene amplification is associated with poor prognosis in colorectal carcinoma

BACKGROUND: Recently, the anaplastic lymphoma kinase (ALK) has been found to be altered in several solid and haematological tumours. ALK gene copy number changes and mutations in colorectal cancers (CRCs) are not well characterised. We aimed to study the prevalence of ALK copy number changes, transl...

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Autors principals: Bavi, P, Jehan, Z, Bu, R, Prabhakaran, S, Al-Sanea, N, Al-Dayel, F, Al-Assiri, M, Al-Halouly, T, Sairafi, R, Uddin, S, Al-Kuraya, K S
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
Matèries:
Genetics and Genomics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833224/
https://ncbi.nlm.nih.gov/pubmed/24129244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.641
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