Infiltrating macrophages promote prostate tumorigenesis via modulating androgen receptor-mediated CCL4-STAT3 signaling

Infiltrating macrophages are a key component of inflammation during tumorigenesis, but the direct evidence of such linkage remains unclear. We report here that persistent co-culturing of immortalized prostate epithelial cells with macrophages, without adding any carcinogens, induces prostate tumorig...

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Bibliographic Details
Main Authors: Fang, Lei-Ya, Izumi, Kouji, Lai, Kuo-Pao, Liang, Liang, Li, Lei, Miyamoto, Hiroshi, Lin, Wen-Jye, Chang, Chawnshang
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833080/
https://ncbi.nlm.nih.gov/pubmed/23878190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-3228
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