Comparative Analysis of the α-Like Globin Clusters in Mouse, Rat, and Human Chromosomes Indicates a Mechanism Underlying Breaks in Conserved Synteny

We have sequenced and fully annotated a 65,871-bp region of mouse Chromosome 17 including the Hba-ps4 α-globin pseudogene. Comparative sequence analysis with the functional α-globin loci at human Chromosome 16p13.3 and mouse Chromosome 11 shows that this segment of mouse Chromosome 17 contains a gro...

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Veröffentlicht in:	Genome Res
Hauptverfasser:	Tufarelli, Cristina, Hardison, Ross, Miller, Webb, Hughes, Jim, Clark, Kevin, Ventress, Nicki, Frischauf, Anna Maria, Higgs, Douglas R.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Cold Spring Harbor Laboratory Press 2004
Schlagworte:	Letters
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383306/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15060003/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gr.2143604
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