Salamander-Derived, Human-Optimized nAG Protein Suppresses Collagen Synthesis and Increases Collagen Degradation in Primary Human Fibroblasts

Unlike humans, salamanders regrow their amputated limbs. Regeneration depends on the presence of regenerating axons which upregulate the expression of newt anterior gradient (nAG) protein. We had the hypothesis that nAG might have an inhibitory effect on collagen production since excessive collagen...

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Bibliografiska uppgifter
Huvudupphovsmän: Al-Qattan, Mohammad M., Shier, Medhat K., Abd-AlWahed, Mervat M., Mawlana, Ola H., El-Wetidy, Mohammed S., Bagayawa, Reginald S., Ali, Hebatallah H., Al-Nbaheen, May S., Aldahmash, Abdullah M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Hindawi Publishing Corporation 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833026/
https://ncbi.nlm.nih.gov/pubmed/24288677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/384091
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