Loss of PTEN Expression Is Associated with Recurrence and Poor Prognosis in Patients with Pancreatic Ductal Adenocarcinoma

Phosphatase and tensin homolog (PTEN) is a tumor suppressor in the AKT/mTOR pathway. Animal model studies have shown that loss of PTEN function is involved in the progression of pancreatic cancer. However, the prognostic significance of loss of PTEN expression in pancreatic cancer is unclear. PTEN e...

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Autori principali: Foo, Wai Chin, Rashid, Asif, Wang, Hua, Katz, Matthew H., Lee, Jeffrey E, Pisters, Peter W, Wolff, Robert A., Abbruzzese, James L., Fleming, Jason B, Wang, Huamin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832989/
https://ncbi.nlm.nih.gov/pubmed/23260327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humpath.2012.09.001
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