Transcriptional Regulation of Δ6-Desaturase by Peroxisome Proliferative-Activated Receptor δ Agonist in Human Pancreatic Cancer Cells: Role of MEK/ERK1/2 Pathway

The Δ6-desaturase (Δ6D), also known as fatty acid desaturase 2, is a regulatory enzyme in de novo fatty acid synthesis, which has been linked to obesity and diabetes. The aim of the present study was to investigate the effect of peroxisome proliferative-activated receptor δ (PPARδ) agonist and MEK/E...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Darabi, Maryam, Byagowi, Shima, Fayezi, Shabnam, Darabi, Masoud, Mirshahvaladi, Shahab, Sahmani, Mehdi
التنسيق: Artigo
اللغة:Inglês
منشور في: Hindawi Publishing Corporation 2013
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832962/
https://ncbi.nlm.nih.gov/pubmed/24294133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/607524
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