טוען...
A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis
Rheumatoid arthritis (RA) is strongly associated with the human leukocyte antigen (HLA)-DRB1 locus that possesses the shared susceptibility epitope (SE) and the citrullination of self-antigens. We show how citrullinated aggrecan and vimentin epitopes bind to HLA-DRB1*04:01/04. Citrulline was accommo...
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Main Authors: | , , , , , , , , , , , , , , , , |
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פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
The Rockefeller University Press
2013
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גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3832918/ https://ncbi.nlm.nih.gov/pubmed/24190431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20131241 |
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