A type I IFN–Flt3 ligand axis augments plasmacytoid dendritic cell development from common lymphoid progenitors

During infections and inflammation, plasmacytoid dendritic cells (pDCs) are the most potent type I interferon (IFN-I)–producing cells. However, the developmental origin of pDCs and the signals dictating pDC generation remain incompletely understood. Here, we report a synergistic role for IFN-I and F...

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Autores principales: Chen, Yi-Ling, Chen, Ting-Ting, Pai, Li-Mei, Wesoly, Joanna, Bluyssen, Hans A.R., Lee, Chien-Kuo
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2013
Materias:
Brief Definitive Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832917/
https://ncbi.nlm.nih.gov/pubmed/24145513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20130536
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