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Structural basis for the MukB-topoisomerase IV interaction and its functional implications in vivo

Chromosome partitioning in Escherichia coli is assisted by two interacting proteins, topoisomerase (topo) IV and MukB. MukB stimulates the relaxation of negative supercoils by topo IV; to understand the mechanism of their action and to define this functional interplay, we determined the crystal stru...

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Detalhes bibliográficos
Main Authors: Vos, Seychelle M, Stewart, Nichole K, Oakley, Martha G, Berger, James M
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832749/
https://ncbi.nlm.nih.gov/pubmed/24097060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.218
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