Effects of N-Acetylcysteine in Ozone-Induced Chronic Obstructive Pulmonary Disease Model

INTRODUCTION: Chronic exposure to high levels of ozone induces emphysema and chronic inflammation in mice. We determined the recovery from ozone-induced injury and whether an antioxidant, N-acetylcysteine (NAC), could prevent or reverse the lung damage. METHODS: Mice were exposed to ozone (2.5 ppm,...

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Autors principals: Li, Feng, Wiegman, Cornelis, Seiffert, Joanna M., Zhu, Jie, Clarke, Colin, Chang, Yan, Bhavsar, Pank, Adcock, Ian, Zhang, Junfeng, Zhou, Xin, Chung, Kian Fan
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832609/
https://ncbi.nlm.nih.gov/pubmed/24260479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080782
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