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Gli Activity Is Critical at Multiple Stages of Embryonic Mammary and Nipple Development

Gli3 is a transcriptional regulator of Hedgehog (Hh) signaling that functions as a repressor (Gli3(R)) or activator (Gli3(A)) depending upon cellular context. Previously, we have shown that Gli3(R) is required for the formation of mammary placodes #3 and #5. Here, we report that this early loss of G...

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Detalhes bibliográficos
Main Authors: Chandramouli, Anupama, Hatsell, Sarah J., Pinderhughes, Alicia, Koetz, Lisa, Cowin, Pamela
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832531/
https://ncbi.nlm.nih.gov/pubmed/24260306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079845
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