Targeting JNK by a New Curcumin Analog to Inhibit NF-kB-Mediated Expression of Cell Adhesion Molecules Attenuates Renal Macrophage Infiltration and Injury in Diabetic Mice

Macrophage infiltration contributes to the pathogenesis of diabetic renal injury. However, the regulatory mechanisms between macrophage infiltration and epithelial cell activation are still unclear. Our previous study found that C66, a novel curcumin analog, was able to inhibit inflammatory cytokine...

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Main Authors: Pan, Yong, Zhang, Xiuhua, Wang, Yi, Cai, Lu, Ren, Luqing, Tang, Longguang, Wang, Jingying, Zhao, Yunjie, Wang, Yonggang, Liu, Quan, Li, Xiaokun, Liang, Guang
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832497/
https://ncbi.nlm.nih.gov/pubmed/24260158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079084
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