Evaluation of OspA Vaccination-Induced Serological Correlates of Protection against Lyme Borreliosis in a Mouse Model

BACKGROUND: For clinical development of a novel multivalent OspA vaccine against Lyme borreliosis, serological assays are required which can be used to establish immune correlates of protection against infection with Borrelia. METHODS: Four assays (an OspA IgG ELISA, a competitive inhibition (CI) EL...

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Autors principals: Schwendinger, Michael G., O'Rourke, Maria, Traweger, Andreas, Savidis-Dacho, Helga, Pilz, Andreas, Portsmouth, Daniel, Livey, Ian, Barrett, P. Noel, Crowe, Brian A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832494/
https://ncbi.nlm.nih.gov/pubmed/24260146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079022
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