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Multiple Transcripts from a 3′-UTR Reporter Vary in Sensitivity to Nonsense-Mediated mRNA Decay in Saccharomyces cerevisiae
Nonsense-mediated mRNA decay (NMD) causes accelerated transcript degradation when a premature translation termination codon disrupts the open reading frame (ORF). Although endogenous transcripts that have uninterrupted ORFs are typically insensitive to NMD, some can nonetheless become prone to NMD w...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3832414/ https://ncbi.nlm.nih.gov/pubmed/24260526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080981 |
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