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Tolerance of Escherichia coli to Fluoroquinolone Antibiotics Depends on Specific Components of the SOS Response Pathway

Bacteria exposed to bactericidal fluoroquinolone (FQ) antibiotics can survive without becoming genetically resistant. Survival of these phenotypically resistant cells, commonly called “persisters,” depends on the SOS gene network. We have examined mutants in all known SOS-regulated genes to identify...

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Bibliografiske detaljer
Main Authors: Theodore, Alyssa, Lewis, Kim, Vulić, Marin
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832272/
https://ncbi.nlm.nih.gov/pubmed/24077306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.152306
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