Extracellular secretion of protease HtrA from Campylobacter jejuni is highly efficient and independent of its protease activity and flagellum

The serine protease HtrA of C. jejuni has been identified as a novel secreted virulence factor which opens cell-to-cell junctions by cleaving E-cadherin. Efficient C. jejuni transmigration across polarized human epithelial cells requires the intact flagellum and HtrA; however, the mechanism of HtrA...

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Autores principales: Boehm, Manja, Haenel, Ingrid, Hoy, Benjamin, Brøndsted, Lone, Smith, Todd G., Hoover, Timothy, Wessler, Silja, Tegtmeyer, Nicole
Formato: Artigo
Lenguaje:Inglês
Publicado: Akadémiai Kiadó 2013
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832103/
https://ncbi.nlm.nih.gov/pubmed/24265934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1556/EuJMI.3.2013.3.3
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