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Neisseria meningitidis expresses a single 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase that is inhibited primarily by phenylalanine

Neisseria meningitidis is the causative agent of meningitis and meningococcal septicemia is a major cause of disease worldwide, resulting in brain damage and hearing loss, and can be fatal in a large proportion of cases. The enzyme 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase (DAH7PS) cataly...

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Autors principals: Cross, Penelope J, Pietersma, Amy L, Allison, Timothy M, Wilson-Coutts, Sarah M, Cochrane, Fiona C, Parker, Emily J
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832045/
https://ncbi.nlm.nih.gov/pubmed/23754471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2293
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