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The crystal structures of the tri-functional Chloroflexus aurantiacus and bi-functional Rhodobacter sphaeroides malyl-CoA lyases and comparison with CitE-like superfamily enzymes and malate synthases

BACKGROUND: Malyl-CoA lyase (MCL) is a promiscuous carbon-carbon bond lyase that catalyzes the reversible cleavage of structurally related Coenzyme A (CoA) thioesters. This enzyme plays a crucial, multifunctional role in the 3-hydroxypropionate bi-cycle for autotrophic CO(2) fixation in Chloroflexus...

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Detalhes bibliográficos
Main Authors: Zarzycki, Jan, Kerfeld, Cheryl A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832036/
https://ncbi.nlm.nih.gov/pubmed/24206647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-13-28
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