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ChIP-seq in steatohepatitis and normal liver tissue identifies candidate disease mechanisms related to progression to cancer

BACKGROUND: Steatohepatitis occurs in alcoholic liver disease and may progress to liver cirrhosis and hepatocellular carcinoma. Its molecular pathogenesis is to a large degree unknown. Histone modifications play a key role in transcriptional regulations as marks for silencing and activation of gene...

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Detalhes bibliográficos
Main Authors: Bysani, Madhusudhan, Wallerman, Ola, Bornelöv, Susanne, Zatloukal, Kurt, Komorowski, Jan, Wadelius, Claes
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831757/
https://ncbi.nlm.nih.gov/pubmed/24206787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-6-50
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