Quercetin and allopurinol reduce liver thioredoxin-interacting protein to alleviate inflammation and lipid accumulation in diabetic rats

BACKGROUND AND PURPOSE: Thioredoxin-interacting protein (TXNIP), a regulator of cellular oxidative stress, has been associated with activation of NOD-like receptor 3 (NLRP3) inflammasome, inflammation and lipid metabolism, suggesting it has a role in the pathogenesis of non-alcoholic fatty liver dis...

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Detalhes bibliográficos
Main Authors: Wang, Wei, Wang, Chuang, Ding, Xiao-Qin, Pan, Ying, Gu, Ting-Ting, Wang, Ming-Xing, Liu, Yang-Liu, Wang, Fu-Meng, Wang, Shui-Juan, Kong, Ling-Dong
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831713/
https://ncbi.nlm.nih.gov/pubmed/23647015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12226
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