Asiatic Acid Isolated From Centella Asiatica Inhibits TGF-β1-induced Collagen Expression in Human Keloid Fibroblasts via PPAR-γ Activation

Keloids are fibroproliferative disorders characterized by exuberant extracellular matrix deposition and transforming growth factor (TGF)-β/Smad pathway plays a pivotal role in keloid pathogenesis. Centella asiatica extract has been applied in scar management for ages. As one of its major components,...

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Detalhes bibliográficos
Main Authors: Bian, Difei, Zhang, Jizhou, Wu, Xin, Dou, Yannong, Yang, Yan, Tan, Qian, Xia, Yufeng, Gong, Zhunan, Dai, Yue
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2013
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831116/
https://ncbi.nlm.nih.gov/pubmed/24250248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.7273
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