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An association between the PTGS2 rs5275 polymorphism and colorectal cancer risk in families with inherited non-syndromic predisposition

Recently our group completed a genome-wide linkage study investigating Australian and Spanish families with inherited risk of colorectal cancer (CRC). A minor linkage peak from that study located on chromosome 1 correlates with the location of a known CRC risk-modifying gene, prostaglandin synthase...

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Hlavní autoři: Ross, Jason, Lockett, Linda, Brookes, Diana, Tabor, Bruce, Duesing, Konsta, Buckley, Michael, Lockett, Trevor, Molloy, Peter, Macrae, Finlay, Young, Graeme, Blanco, Ignacio, Capella, Gabriel, Hannan, Garry N
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831072/
https://ncbi.nlm.nih.gov/pubmed/23531863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2013.53
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